





Zebra ZD421-HC 4-inch Healthcare Desktop Label Printer
Safe, easy, advanced healthcare printing
Key Features:
- Print Width: 4 in.
- Print Technology: Direct Thermal, Thermal Transfer Roll, Thermal Transfer Cartridge
- Print Speed: 4 ips (102 mm/s), 6 ips (152 mm/s)
- Print Resolution: 203 dpi (8 dot/mm), 300 dpi (12 dot/mm)
- Connectivity: Wi-Fi 6 (802.11ax) with Bluetooth 5.3 (optional), Wi-Fi 5 (802.11ac) with Bluetooth 4.1 (optional), Bluetooth 5.0, Bluetooth Low Energy
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Description
Zebra ZD421-HC 4-inch Healthcare Desktop Label Printer
Designed for Clinical Environments
Constructed from disinfectant-ready, UV-resistant plastics with sealed buttons, the ZD421โHC is engineered for easy sanitization and reduced germ exposureโperfect for hospitals, clinics, and labs.
High-Quality Thermal Printing
Supports both direct thermal and thermal transfer (including ribbon cartridge) options with resolutions of 203โฏdpi standard or optional 300โฏdpi. Achieves print speeds up to 6โฏips at 203โฏdpi, delivering sharp, legible labels for patient care.
Flexible Connectivity
Comes standard with USB (2.0 and USB Host), optional field-installable Ethernet, RS-232 serial, WiโFi 802.11ac, and Bluetooth 4.1 with BLE. Mobile app setup via Bluetooth LE supported.
Robust & Compact Design
Featuring Zebraโs OpenACCESSโข media loading, dual-wall frame, and ENERGY STAR certification, this printer offers a compact footprint (approx. 220โฏรโฏ177โฏรโฏ151โฏmm) and reliability.
Versatile Media Handling
Accepts media widths from ~15โฏmm to 118โฏmm, roll-fed or fan-fold, with options for peeler and cutter. It supports wristbands, tags, continuous receipt paperโideal for healthcare workflows.
Powered by Zebra Print DNA
Includes powerful operating system with support for ZPL II/EPL2, PDF Direct, Unicode, and remote management tools, plus PrintSecure data protection.
Optional Portability
Can be equipped with a 2750โฏmAh battery and carrying case for cart or bedside mobility.
Healthcare-Ready Approvals
Includes IECโฏ60601โ1 certified power supply tailored specifically for healthcare environments.

















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